Right-to-left Shunting (RLS) through a Patent Foramen Ovale (PFO) is a known risk factor for ischemic stroke and commonly screened in cases of cryptogenic stroke. With recent evidence linking the significance of PFO closure for reduction of recurrent stroke, there is a need for broader access to accurate, easily repeatable tools to identify high-risk patients considered for transcatheter PFO closure.
The use of a transcranial Doppler (TCD) bubble study has proven to be a highly valuable, non-invasive tool due to its high sensitivity and specificity in detecting and grading the physiological nature of a PFO.
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